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Spleen

Function of Spleen

- RBC maintaince
- Pathogen Screening

Structures Of Spleen

graph TD
    X{spleen} ==> X1[Red pulp = RBC maintainece region];
    X ==> X2[White Pulp = Lymphocyte Region];

Spleen -Red/White Pulp

graph TD
    X[Splenic Artery] ==>|brenches into| X1[Trabecular Artery];
    X1 ==>|branches to | X2{Central Artery};
    X2 ==>|<mark>Surrounded by pipe like</mark>| X2a[PALS];
    X2a ==>|Central artery then branches into  Marginal Sinuses with Segmented Endothelium 
     <mark>Surrounding a Nodule</mark>| X2a1[Splenic Nodule B-Cells rich Germinal Centres region];
    Y[<ul>White Pulp<ul>]
    X2a ==> Y;
    X2a1 ==>Y;  
    X3x{central artery After white Pulp} ==>|into| X3[Penicilliar arterioles];
    X3 ==> X3a[Open Circulation];
    X3 ==> X4[closed Circulation];
    X3a ==> X3a11[Penicilliar arterials opens up to Splenic Cords rich in macropages];
    X4 ==>|<mark> A mesh That al:octicons-arrow-down-24: perfect RBC  to enter ,made up of long endothelial cells supported by cross Basement Membrane- like wine barrel </mark>| X3b[Splenic Sinusoids];
    X3b ==>|fit RBC enters back | X3b1a[closed Circulation = back to vein ];
    X3b ==>|failed to fit in Splenic Sinusoids| X3b1b[eaten by macrophages in Splenic Cords];