Connective Tissue Classification

graph TD
    1{Connectissue types} ==> X(Proper-connective tissue);
    1 ==> 2{Supportive connective tissue};
    1 ==> 3{fluid connective tissue};
    X ==> Xa{loose};
    Xa ==>Xa1[loose = eg;Endo-nerium];
    Xa ==> Xa2[loose + adipose];
    Xa ==> Xa3[loose + reticular collagen @ spleen thymus];
    X ==> Y{Dense};
    Y ==> Ya[Dense connective tissue];
    Ya ==> Ya1[dense + regular];
    Ya ==> Ya2[dense + irregular];
    Ya ==> Ya3[dense + elastic];
    2 ==> 2a{bone};
    2a ==> 2a1[spongy bone];
    2a ==> 2ab[compact bone];
    2 ==> 2b{cartilage};
    2b ==> 2b1[hyaline];
    2b ==> 2b2[Fibrocartilage];
    2b ==>2b3[elastic cartilage];
    3 ==> 3a[blood];

Proper Connective Tissue

graph TD
    A[Proper Connective tissue under Epithelim] ==> 1{Fibroblast};
    A ==> 2{Travelling cells};
    1 ==>|produces| 1a(Extracellular Matrix);
    1a ==>|contains| 1aa[Ground substance];
    1a ==>|contains| 1ab[fibres];
    1ab ==>1ab1[Collagen];
    1ab ==> 1ab2[Elastin];
    2 ==> 2a[T/B-Lymphocytes,NK Cells];

other Types of Connective tissue cells

Generate = Blast MAintain = cyte

1. Proper Connective tissue = Fibro
   • Generate = Fibro- blast
2. Bone = OSteo
   • Generate = OSteo- blast
3. Cartilage = Chondroi
   • Generate = Chondrio- blast
4. Fat = adipose
   • Generate = Adipose-blast

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Collagen

• Provides strength

Ehlers Danlos syndrome

Lysine hydroxyalse deficiency Lysine hydroxylase - adds OH to lysine with Vitamin C

OSteo genesis imperfect/Brittle bone disease

Collagen gene problem

Types of Collagen

• 100 types of collagen

Most important collagens

graph TD
    1[Important collagen] ==> A[Type 1]
    1 ==> B[Type 2];
    B ==> b2[cartilage];
    A ==>a1[on bones];
    1 ==> C[Type 3];
    C ==> c1[reticular fibres of lymph,thumbs,spleen];
    1 ==>D[Type 4];
    D ==> d1[Basement membrane];

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Elastin

• Provides Elasticity

MarfanSyndrome

Abnormal elastin arrangement ==> loss of elasticity