Chemo-agents for Cancer¶

Soft tissue¶

methotrexate + Adriamycin.

Desmoid¶

Tamoxifen.

oral ca¶

 in + lymph => 5-FU, cisplatin

Breast¶

1.CAF/CMF  - not used 
    C= Cyclophosphamide.
    A = adrinamycin
    F = 5-FU
    M = methotraxate
    T=  Taxanes (Paclitaxel/Docetaxel). 
    E = epirubicin.

2.Her2Neu -ve
    4 cycles of AC/EC then ->4cylces T

3.Her2nue + 
    6cycles of TCH+P

    T: Taxanes. 
    C: Carboplatin.

    ### Anti-Her2nu  
    H: Herceptin.
    P: Pertuzumab

Thyroid¶

Chemotherapy:Doxirubicin
anaplstic mets = Dabrafenib[tyrosine kinases inhib]

Adrenal Neuroblastoma¶

etoposide & cistplatin

Carcinoid Maligancy / Mets¶

Cisplatin ,5-Fu

malignant pheochromo¶

dacarbazine & vincristine

GI¶

Esophagus¶

Gemcitabine, Cisplatin, 5-FU.

STomach¶

5-Fu,Cisplatin

appendicular high grade mucinous ca¶

mitomycin-C, Paclitaxel via hyperthermic locally
then Pacli + carboplatin via iv

liver¶

Vasucalr Agrassive HCC¶

Sorafenib - Tyrosine kinase inhibitor

Advamced HCC mets¶

Pembrolizumab/Nevolumab

Colo-rectal can metsto liver¶

Bevacizumab (monoclonal antibody against VEGP).

GB cancer¶

Gemcitibine

Pancreatic ca¶

Gemcitabine + capecitabine
mFolfirinox
Nabpaclitaxel - unresectable ca
streptozocin = Insulinoma mets
5-FU ,Streptozosin = Gastrinoma in D1
Streptozosin = non functional pancretic tumors with Mets

Endometrial Ca¶

carboplatin and Paclitaxel for 6cycles

Colon ca¶

FOLFOX : 5-Fu ,Folinic acid ,oxiplatinum
FOLFIRI : 5-Fu ,Folinic acid, irinotican
CAPFOX : capecitabine. oxiplatinum

Colon ca Immunitherpay¶

Bevacizumab : VEGF inhibitor
etuximab : EGFR inhibitor
antimumab : EGFR inhibitor
evozumab , Pembrolizumab : PDL1 inhibition @ Micro-statellite instability