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Cell Adaptation

graph TD
    X[Normal cell] ==>|stress| X1[Cell adaptation];
    X1 ==> X1a[Hypertrophy] & X1b[Hyperplasia] & X1c[Metaplasia] &  X1d[Dyspalsia] & X1e[Atrophy];

1. Hyperplasia

  1. Cells that can multiple
Physiologic Patholagic
Hormonal Physiologic Hyperplasis - Breast during Puberty,Uterus Smooth muscle Endometrial hyperplasia cancer from estranged hypersection
Compensatory Physiologic Hyperplasis - Liver cell hyperplasia after liver Transplant Benign Prostatic Hyperplsia

Hypertrophy

  1. Mainly cells that cannot Replicate, and few exception
Physiologic Pathologic
Physiologic Hypertrophy of SM of Uterus during pregnancy Hypertrophy of Left ventricle due to Aortic stenosis, HTN

Atrophy

  • Opposite to both Hypertrophy,due to loss of Function(limb atrophy after paralysis),insufficient supply of Nutrients,Physiology Atrophy(Endometrium after menopause_
  • Cell size(Lysosomal degradation and Autophagy)

Metaplsia

  • Change for one cell type to a better cell type to withstand the new stress
  • Sxamples > Stratified Squamous Epithelium to Non-Cliated Columnar Epithelium due to Acid reflex > Ciliated Columnar epithelium to Statified Squmous epithelium due to continuous cigarette smoking > Myositis Ostification replacement of SKeletal Muscle with Bone tissue due extensive damage to muscles

  • Uncontrolled Metaplsis leads to carcinoma

Dysplasia

  • Disorder growth of cells
  • Precursor to Cancer
  • Can be reversed by removal of Stress