Orthomyxo Viruses

- segmented

Types of Viruses

1. Influenza A (avian and human infections)
2. Influenza B (infect humans only)

Virulance

1. Hemagglutinis --> helps entry into cells by binding to surface proteins
2. Neuraminidase ---> helps exit out of infected cells

Pathogenesis

1. Antigenic drift --> RNA polymerase error in readind leads to new Virulancee protein
2. Antigenic shift --> Exchange of virulance factor between 2 stains of Influenza