Chromosme location

Hemoglobin gene location

1. alpha chain - 16
2. beta chain - 11

Leukemia

1. t(15;17) Acute Promyelotic Leukemia - Retanoic acid receptor problem
2. B-ALL - t(12:21) good Prognosis
3. B-ALL - t(9:22) bad CML
4. CML - t(9:22) philadelphia Chromosome-Tyrosine Kinase receptor activity
5. Polycythemai Vera - JAk₂ kinase mutation
6. Essential Thrombocytopenia - JAK₂ kinase mutation