Anaphylaxis

Anaphylaxis

Diagnose Anaphylaxis

DXD for Anaphylaxis

Mng

Adrenaline Dosages in Children

Age Group	Dosage
<6 years	0.15 mg IM
6–12 years	0.3 mg IM
>12 years	0.5 mg IM

• If hypotensive > rapid infusion of 1–2L (NS).
• hypotensive Children

  NS in boluses of 20 mL/kg, each over 5–10 minutes, and repeated, as needed. Large volumes of fluid (up to 100 mL/kg) may be required.

Adrenaline Administration for Hypotension

If hypotension persists, follow these steps:

1. Adrenaline Bolus: 0.1–0.5 mg IV in 1:10,000 dilution
2. Adrenaline Infusion:
3. Initial rate: 0.1 µg/kg/min
4. Example: For a 60 kg man, start at 6 µg/min

Antihistamines

• H1 Blockers:
• Chlorpheniramine maleate (Avil): 1–2 mL slow IV/IM
• Promethazine (Phenergan): 25 mg IV/IM stat
• H2 Blockers:
• Ranitidine: 50 mg IV stat, then q8h
• Glucagon 1–5 mg IV over 5 minutes, followed by infusion of 5–15 µg/min is useful in patients on regular β blockers.

Discharge Medications for Stable Patients

Medication	Dose	Frequency	Duration
Levocetirizine	5–10 mg	OD, hs	3–5 days
Ranitidine	150 mg	BD	3–5 days
Prednisolone	0.5 mg/kg	OD	3 days